Friday, June 29, 2018
While self-reported adherence to treatment appears to be high for both systemic lupus erythematosus and vasculitis, patient forgetfulness remains a strong barrier, according to a research.
Diacerein appears to be more effective than glucosamine plus chondroitin for patients with mild-to-moderate knee osteoarthritis, according to a study.
The selective cannabinoid receptor type 2 agonist lenabasum exhibited an acceptable safety profile while improving outcomes in patients with diffuse cutaneous systemic sclerosis, according to results of a phase II study.
Pregnant women with rheumatoid arthritis (RA) are more likely to have premature delivery or baby of low birth weight compared with women without RA, according to a study.
Analysis of pooled data from three phase III trials (SPIRIT-P1, -P2, and -P3) reveals that ixekizumab (IXE), a high-affinity monoclonal antibody that selectively targets interleukin-17A, is a safe treatment for patients with active psoriatic arthritis (PsA), according to a study.
Patients with ankylosing spondylitis (AS) derived a greater benefit from tumor necrosis factor (TNF) inhibitors in terms of less radiographic progression when they also took non-steroidal anti-inflammatory drugs (NSAIDs), suggests a cohort study.
|The selective T cell costimulation modulator abatacept can lead to a rapid improvement in proteinuria, which induces earlier, sustained complete response compared with placebo in patients with active class III or IV lupus nephritis, although the rate of complete response is similar between groups, suggests a study.|
Friday, June 1, 2018
Proprotein convertase subtilisin/kexin 9 (PCSK9) inhibitor is superior to ezetimibe in reducing low-density lipoprotein cholesterol (LDL-C), with or without statin therapy, according to a study. Additionally, PCSK9 inhibitor shows comparable safety profile.
Non-vitamin K antagonist oral anticoagulants (NOACs) offer better efficacy and safety, especially in terms of risk of stroke and major bleeding, respectively than warfarin for Asian patients with atrial fibrillation (AF), according to a presentation at APSC 2018. The benefits were also greater for Asians compared with non-Asians.
Implementation of an electronic national early warning score information system may cut the rate of in-hospital cardiac arrest, as well as improve the rate of survival to discharge, as shown in a study.
Even in the absence of peripheral arterial disease, a lower ankle-brachial index is significantly associated with larger declines in cognitive function, according to a study.
Malay ethnicity, male gender, smoking and having hyperlipidemia are associated with an increased risk of coronary calcification, according to a study.
The appropriate use of sodium/glucose cotransporter 2 inhibitors (SGLT2i) may prevent serious adverse events (SAEs) among Japanese patients with type 2 diabetes (T2D), according to a retrospective analysis of data from medical claim database.
The use of the sodium-glucose cotransporter 2 (SGLT2) inhibitor dapagliflozin in patients with type 2 diabetes (T2D) and moderate renal impairment provides benefits beyond glucose lowering, with no new safety signals, in phase III DERIVE* study.